Interaction Checker

Rilpivirine

Wednesday 19 October 2011

Interactions with rilpivirine and comedications are now available on the website and the HIV iCharts app.  The printable versions of the charts and HIV-Charts2Go have also been updated to include these new interactions.

Rilpivirine is primarily metabolized by cytochrome P450 (CYP)3A - drugs that induce or inhibit CYP3A may affect the clearance of rilpivirine. At the recommended dose of 25 mg once daily, rilpivirine is not likely to have a clinically relevant effect on the exposure of medicinal products metabolised by CYP enzymes.
 
Rilipivirine was licensed a few months ago by the FDA in the US and has been recommended for approval in Europe by the EMA.  Rilpivirine is marketed as Edurant® and is also available in as a coformulation (Complera®, Eviplera®) with emtricitabine and tenofovir.
 
SPONSORS
Sponsor logo janssen Sponsor logo gilead Sponsor logo msd Sponsor logo viiv Sponsor logo abbvie Sponsor logo bristol myers squibb
EDITORIAL SPONSORS
Bhiva Glasgow Eacs logo 2014