Coadministration has not been studied. Coadministration with systemic immunosuppressants should be done with caution because plasma concentrations of the immunosuppressant may be decreased when coadministered with etravirine.
Intelence Summary of Product Characteristics, Janssen-Cilag Ltd, March 2019.

Etravirine and systemic immunosuppressants should be co-administered with caution because plasma concentrations of tacrolimus may be affected.
Intelence US Prescribing Information, Janssen Therapeutics, July 2019.