Coadministration is expected to increase quetiapine concentrations. Initiation of Genvoya in patients taking quetiapine: Consider alternative antiretroviral therapy to avoid increases in quetiapine exposure. If coadministration is necessary, reduce the quetiapine dose to 1/6 of the current dose and monitor for quetiapine-associated adverse reactions. Refer to the quetiapine prescribing information for recommendations on adverse reaction monitoring. Initiation of quetiapine in patients taking Genvoya: Refer to the quetiapine prescribing information for initial dosing and titration of quetiapine.