The NNRTI charts have been updated to reflect changes made in the wording or data presented in the most recent versions of the European Summaries of Product Characteristics and the US Prescribing Information.
New or amended interaction data have been added as follows:
Delavirdine Prescribing Information, updated from 2001 to February 2006 (carbamazepine, didanosine, diltiazem, fluoxetine, fluticasone, ketoconazole, nelfinavir, phenobarbital, phenytoin, rifabutin, saquinavir, sirolimus, trimethoprim/sulfamethoxazole, zidovudine)
Efavirenz SPC, updated from December 2005 to January 2007 (amprenavir, atazanavir, diltiazem, indinavir, itraconazole, lopinavir, nicardipine, nifedipine, ritonavir, saquinavir, verapamil)
Efavirenz Prescribing Information, updated from March 2006 to January 2007 (atorvastatin, bepridil, diltiazem, itraconazole, pimozide, pravastatin, rifampicin, simvastatin, voriconazole)
Nevirapine SPC, updated from November 2005 to January 2007 (clarithromycin, efavirenz, ethinylestradiol, indinavir, itraconazole, ketoconazole, methadone, nelfinavir, progesterone/progestogen, rifabutin, ritonavir, saquinavir, stavudine, zidovudine)
No changes were made for the nevirapine Prescribing Information as a new version has not been published since January 2005. Changes have not been required for the printable versions of the charts.